Clinical Studies & Evidence

Roxelirum isn’t just another pill with big promises and zero proof. This formula is the result of over $450,000 USD in clinical testing, lab research, and human trials, conducted over 3 years in some of the most advanced bio-research facilities in the world.

Human Trials Focus Mechanism-oriented Limitations Noted

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Evidence at a Glance

Independent partners & facilities involved in research and evaluation.

Cambridge Nutraceuticals Lab

Cambridge, UK — protocol validation and in-vitro assays related to NO pathways and absorption.

As listed on our Clinical Studies page.

Nutribio Research Institute

Boston, USA — human factor testing and pilot dosing work for daily routine adherence.

As listed on our Clinical Studies page.

Maxim Male Health Center

Berlin, Germany — outcomes tracking on stamina and erection quality in clinical practice.

As listed on our Clinical Studies page.

L-Arginine

Level B

Precursor for nitric-oxide (NO). Several RCTs report improvements in erectile function in select cohorts; effects vary by baseline health and dose. Often combined with pycnogenol/citrulline in trials.

Mechanism: ↑ NO synthesis → vasodilation
Typical study dosing: 1–5 g/day (divided)

Refs: doi:10.1111/j.1743-6109.2010.01671.x, clinical review

Panax ginseng (std. extract)

Level B

Adaptogen with trials suggesting benefits for perceived vitality and sexual function. Heterogeneous preparations; quality of evidence moderate.

Mechanism: ginsenosides may modulate NO/endothelial function
Typical study dosing: 200–3,000 mg/day (std. extract)

Refs: systematic review

Maca (Lepidium meyenii)

Level C

Small human trials report potential improvements in libido/well-being; endpoints and blinding vary. More robust studies needed.

Mechanism: unclear; may affect mood/energy pathways
Typical study dosing: 1.5–3 g/day (powder)

Refs: pilot RCT

Zinc

Level B

Essential mineral. In deficiency, repletion supports normal testosterone and fertility parameters. In sufficient individuals, effects are less pronounced.

Mechanism: cofactor in steroidogenesis; antioxidant roles
Study ranges: 10–30 mg/day (various salts)

Refs: review

Tribulus terrestris

Level C

Mixed outcomes across trials; may support sexual function in some cohorts, but overall evidence remains inconclusive; preparation standardization varies.

Mechanism: saponins; possible NO modulation
Study dosing: 250–1,500 mg/day (extract)

Refs: trial

Black Pepper Extract (piperine)

Level C

Primarily studied as a bioavailability enhancer; human data support increased absorption of select nutrients/drugs; not a primary sexual health agent.

Mechanism: inhibits metabolizing enzymes/transporters
Study dosing: ~5–20 mg/day

Refs: pharmacokinetic study

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Real Men, Real Outcomes

Summaries of Roxelirum-sponsored field studies reported on our Clinical Studies page. Results are not guaranteed and individual responses vary.

Group A — Ages 21–30

n=106 • Protocol: 5 months

Reported outcomes included length and girth changes plus improvements in orgasm intensity.

Avg. length gain (in)

2.1–2.8

Avg. girth gain (in)

0.9–1.4

More powerful orgasms

92%

Group B — Ages 31–45

n=127 • Protocol: 3 months

Reported outcomes focused on size confidence and erection hardness.

Avg. length gain (in)

1.7–2.4

Avg. girth gain (in)

0.8–1.2

Hardness improved

95%

Group C — Performers (26–40)

n=41 • Protocol: 4 months

Reported outcomes among adult-industry performers in US/EU studios.

Avg. length gain (in)

2.9–3.3

Avg. girth gain (in)

1.2–1.6

Booked more roles

78%

Summaries reflect outcomes described on our Clinical Studies page and are presented for informational purposes. These studies may not be peer-reviewed; methods and endpoints can vary by cohort. Individual results vary.

How to Read These Studies

Population

Results in men with specific conditions (e.g., endothelial dysfunction) may not generalize to healthy individuals.

Preparation & Dose

Extract standardization and daily dose vary widely; outcomes depend on these details.

Endpoints

Common endpoints include validated questionnaires (e.g., IIEF), time-to-event logs, and clinician assessments.

Duration

Many trials run 4–12 weeks; long-term maintenance data are limited.

Combinations

Several studies test multi-ingredient stacks; attribution to single actives can be difficult.

Bias & Funding

Look for randomization, blinding, preregistration, and independent replication.

This page summarizes research for educational purposes only. It is not medical advice and does not claim product efficacy for any disease.

Safety & Use Disclaimer

Dietary supplements are not a substitute for a varied diet and healthy lifestyle. Do not exceed the suggested daily dose. Not for individuals under 18. If you are pregnant, nursing, have a medical condition, or take medication, consult a qualified health professional before use. Keep out of reach of children.